Saturday, December 28, 2019

Strategic Goals And Tactical Goals Essay - 1293 Words

Leadership generally take for granted that leadership concepts or communicated down to departments within organizations; however, this often not so true. Regrettably, some organizations become misunderstood by the problem of miscommunication. Therefore, by setting strategic goals and tactical goals can organizations create strategic communication. Strategic goals within organizations, let leaders set goals for overall objectives for their organization; therefore, communication organization goals. While tactical goals achieve departmental objectives in the context of overall strategic goals. One of the utmost important direction is leadership to employee communication. Strategic Planning Tools Strategic goals should link into their organization mission or vision statement; therefore, helping with the direction for writing strategic goals. The development of strategic goal describes how their organization will complete their objectives. One insightful practice that can be helpful for determining strategic goals is the strengths, weakness, opportunities and threats (SWOT) analysis. Who it SWOT analysis? It is a structured way to look at internal company principles and external business environment as instruments for determining strategic goals. The idea is to express opportunities and threats, formula strengths and weakness as they relate to opportunities and threats. In addition, another tool for helping to define a strategic goal is Defensive/Offensive Evaluation (DOE)Show MoreRelatedStrategic Planning : Strategic And Tactical Planning874 Words   |  4 Pagesleader must align that vision with goals, but the only way to achieve those goals is through planning. Every p lan needs to operate like a map to success. Strategic and tactical planning, when used correctly, represent planning models that can lead companies forward toward the vision of their leaders, and the attainment of the goals those leaders have developed. Strategic and tactical planning work together. Strategic planning focuses on the big picture, and tactical planning supports that big pictureRead MoreOrganization Planning, Project Management, and Information Technology1319 Words   |  6 Pagesorganization is a challenging and iterative process. The organization must engage in careful and ongoing strategic and tactical planning to ensure that the implemented technology will ultimately be effective and beneficial for its practitioners, staff, and patients. To prepare for this Application Assignment, review the information presented in this week’s Learning Resources on strategic and tactical planning for health information technology and the application of project management methodology by healthRead MoreObjectives And Objectives Of Strategic Planning884 Words   |  4 PagesSetting and Achieving Goals To stay competitive in today’s markets, it is important for companies to determine objectives and develop a plan so as to achieve financial goals. Effective planning is an essential element if a company is to successfully employ change management and implement new processes and procedures that will adjust organization functions and operational assignments in order to meet the desired outcomes. Different methodologies for planning exist to meet the specific needs withinRead MoreLeadership Strategies For A Leader1116 Words   |  5 PagesHelping organizations to create and achieve goals is an essential part of what it means to be a leader. Goals provide direction for followers and set priorities (Leadership Strategies [L.S.], 2015, figure 1). Gen. Colin Powell, former U.S. Secretary of State, claimed that Great leaders are almost always great simplifiers, who can cut through argument, debate and doubt to offer a solution everybody can understand. (Tayor, 2015, para. 4). In es sence, great leaders are able to sift through the distractionsRead MoreGoals And Objectives Of Southwest Airlines1048 Words   |  5 PagesIntroduction A goal is defined as objective to do something measurable within a given period (Davis, 1996). Setting goals is one of the most basic and fundamental elements both at the individual and organizational level. Goals show clear direction and destination that people in an organization need to be moving toward. Goals can be both long-term and short-term, whatever the goal the end objective is always almost the same. To achieve the best results, it is important to improve service deliveryRead MorePlanning : Planning And Management995 Words   |  4 PagesPlanning, in regards to management, can be setting rules and guidelines to complete a goal. Planning can be broken down into different categories or type such as strategic planning, tactical planning, and organizational planning. Some critical components to have when discussing strategic planning is the vision, mission, and values. Initially, a manager starts with strategic planning that gives them a long term goal that will help plan out their next five years. Top manager such as Chief ExecutiveRead MorePlanning Function1703 Words   |  7 Pagesassists an organization in setting goals and determining how to accomplish them best (Allen, 1998). â€Å"Effective planning helps an organization adapt to change by identifying opportunities and avoiding problems. It sets the direction for the other functions of management and for teamwork† (Allen, 1988,  ¶ 1). In order to operate in an efficient and effective manner and to progress with focus and direction, an organization must set goals and develop plans to achieve those goals (Erven, 1999). All managementRead MoreSuccessful Leadership And Organizational Planning898 Words   |  4 Pagesspecialty, organizations must put their time and resources into cre ating plans and goals to achieve any amount of success. There are four main types of planning that many organizations have put to use: strategic, tactical, operational and contingency. I will be describing strategic and tactical planning more in detail as I feel that these two techniques are an essential to any business when they are establishing what their goals need to be. I will discuss the elements that are a part of each planning processRead MoreTypes Of Business Plans : Developing A Business Plan778 Words   |  4 Pagesoperating tool as the business is build and reaches its full potential (Michigan.gov, 2015). There are various types of business plans depending upon the need or project at hand. Some common types of business plan are operational plan, strategic plan, start-up plan and a tactical business plan. The follow paper compares these four types of business plans and looks at their strengths and limitations. Also included in the paper is the best plan that would work for the assigned Collaborative Learning CommunityRead MoreThe Planning Function of Management1206 Words   |  5 Pagesjust one way that managers get together to plan and set goals. All functions of planning must be used by managers in order for the company to succeed; planning helps the company to reach the set goals. All levels of management should use strategic, tactical, operational, and contingency planning. Each level of management tends to plan differently, but at the end of the day, all managers should consult with each other when it comes to setting goals to successfully acting out each plan. â€Å"Managers at all

Friday, December 20, 2019

Learning Style Inventory ( Lsi ) - 1679 Words

Learning Style is a Term that has been of interest in the past few decades in the field of Organizational Behavior. It refers to the way individuals perceive to acquire new skills, knowledge, or education. Scholars of organizational behavior owe David Kolb who is the leading pioneer for the introduction of such term due to his work since 1970`s. David Kolb, a Professor of Organizational Behavior at Case Western Reserve University in Cleveland in the US, established an Experimental theory based on a 17 years search study to develop and enhance the abilities of educators using the Learning Style Inventory (LSI). Coffieldand et al (2004).His aim was to improve traditional teaching for management students in perceiving new learned topics. He†¦show more content†¦xCoffieldand et al mentioned that the authors were keen to emphasize (2000, 43) that ‘no single style has an overwhelming advantage over any other. Each has strengths and weaknesses but the strengths may be especially important in one situation, but not in another. Several scholars disagreed with the idea; that each individual has a unique learning style. They critiqued the work of Kolb, Honey and Mumford, and others who followed on the road of searching for improving and classifying educators in to learning categories. They insisted that naming individual according to learning style prevent them from adapting to new ways of learning. In this paper I used Honey and Mumford questionnaire to determine a suitable development program for a candidate. The candidate will answer the Learning style questionnaire (attached in appendix) as honestly as possible, his educational background and past experience should be taken into consideration in the development program. MATERIAL AND METHODS People in organizations are individuals with deferent behavior, values and personality, whereas organizations â€Å"are group of people who works interdependently toward some purpose† (McShawn,andVonGlinow 4th edition). This workforce diversity needs to be stormed and aligned through what is called evolving employment relationship, thus resulting in increasing their flexibility. Employees should also increase their flexibility throughShow MoreRelatedThe Learning Styles Inventory ( Lsi )921 Words   |  4 PagesIn EDCL 5339, Understanding Self, I took the Learning Styles Inventory (LSI). The results showed that my confirmed strengths are Oppositional, Power, Competitive and Perfectionist. I do not demonstrate strong Oppositional self. I tend to keep an open mind and am willing to listen to others’ opinion. Sometimes, I feel I go along with what others want easily. In my close relationships, I am more opinionated than I am with my colleagues. I would like to develo p the ability to be more analyticalRead MoreThe Learning Style Inventory ( Lsi )1486 Words   |  6 Pagesneed to focus on the concept of individual learning and how it is the building block on my education. In the course we learned about the adult learning process and how we can figure out what techniques and approaches are best suitable for each of us. In the interactive class, we were given worksheets that help us determine what learning style we relate to the most and the benefits that learning style has in an organization. The Learning Style Inventory (LSI) helped me conclude that I gear towards theRead MoreThe Learning Style Inventory ( Lsi )1289 Words   |  6 Pagesresearched on how to put together a project in order to identify the learning styles. The starting point of this scheme was supported by the Kolb learning style inventory (LSI). Finally, they came up with the idea of a questionnaire. They gathered eighty questions together, containing four different learning sty les along with characteristics of the person/s that might fit in. The image below represents the theory along with the learning styles produced. (workpress.com, 2011) Many people will argue thatRead MoreTeaching Strategies For Learning Style Preferences853 Words   |  4 PagesIt is in this article that Beck matches three teaching strategies to learning style preferences. During which he attempts to link the 4MAT system, Dunn’s LSI, and the Renzulli Smith’s LSI to teaching strategies associated to display individual learning preferences linked to the brain’s hemispheres. The 4MAT system and Dunn’s LSI is teacher driven teaching strategies while the Renzulli Smith’s LSI allows student input into their teaching strategies. In linking the 4MAT system to teaching strategiesRead MoreKolb Learning Style Inventory7058 Words   |  29 PagesThe Kolb Learning Style Inventory—Version 3.1 2005 Technical Speciï ¬ cations Alice Y. Kolb Experience Based Learning Systems, Inc. David A. Kolb Case Western Reserve University May 15, 2005 Abstract The Kolb Learning Style Inventory Version 3.1 (KLSI 3.1), revised in 2005, is the latest revision of the original Learning Style Inventory developed by David A. Kolb. Like its predecessors, KLSI 3.1 is based on experiential learning theory (Kolb 1984) and is designed to help individuals identify the wayRead MoreEssay on Gm591 - Life Styles Inventory (Lsi) Results1486 Words   |  6 Pages[pic] GM 591: Life Styles Inventory – Survey results for John Hastings Instructor: Rick Roechnes Date: 09-JAN-2010 TABLE OF CONTENTS 1.0 Introduction 3 2.0 Personal Thinking Styles (Part I) 3 2.1 Primary thinking Back up thinking style 4 2.2 Limiting thinking style 4 3.0 Impact on Management Style (Part II) 5 3.1 Planning 5 3.2 Organizing 6 3.3 Leading 6 3.4 Controlling 6 4.0 Genesis of Personal Styles (Part III) 6 5.0 ConclusionRead MoreThe Academic Success Patterns Of Each Individual Participant1350 Words   |  6 Pageswill be no restrictions on characteristics such as age, race or ethnicity. The learning styles of each participant will be measured at the beginning of each semester, therefore if any of the participant’s learning styles change by the end of semester one, their data will be excluded from the study. Since the study is looking at the academic success patterns of each individual participant, the change in learning style from first to second semester could cause a disruption in the data patterns, whichRead MoreLsi Paper1622 Words   |  7 PagesLSI PAPER Richard Timian Leadership and Organizational Behavior Friday, September 14, 2007 Introduction The Life Styles Inventory (LSI) is a self-assessment diagnostic instrument that measures 12 key thinking patterns, or styles. The LSI promotes performance change and improvement by increasing personal understanding of ones thinking and behavior. By responding to these 240 inventory items, individuals learn exactly where they need to focus their development efforts, without ambiguityRead MoreNotes On Life Styles Inventory979 Words   |  4 Pages Life Styles Inventory Jameka S. Carter Ms. Hallcom 9/14/14 â€Æ' Life Styles Inventory Introduction Individuals possess different skills that have an impact on their thinking and management style. The style varies from individual to individual depending on their opinions, perceptions, thoughts, and skills. The Life Style Inventory is a tool, which can be used to analyze and evaluate the management and leadership skills of an individual. The LSI has different styles and individuals can rateRead MoreLife Styles Inventory852 Words   |  3 Pagesplethora of work experience; therefore, I could not name all five characteristics corresponding to what she asked. Dr. John Doe created the Life Styles Inventory (LSI) assignment; the purpose of this assessment is for people to receive a better understanding of oneself. As stated form the LSI website, Life Styles Inventory (LSI) measures 12 specific styles of patterns of thinking that can either help or hinder a person from reaching his or her potential. The system provides a road map to properly

Thursday, December 12, 2019

Connection Between A Gene Protein Disease †Myassignmenthelp.Com

Question: Discuss About The Connection Between A Gene Protein Disease? Answer: Introducation According to the World Health Organization (1), genes and proteins provide a connection to diseases .Genes determine the order of amino acids used to make proteins, they undergo mutation that cause diseases and gene disorders such as sickle cell anaemia. Furthermore, genes affect the occurrence of non-communicable diseases such as diabetes and cancer (3). Genes and proteins play a major role in the genetics and occurrence of major diseases of the world therefore understating the connection between genes, proteins and disease is of much help to the patients medicine and the society. This essay is aimed at investigating the connection between a gene, protein, and disease, focusing mainly on the link between protein structure and function in the disease and a further analysis of the relevance to patients, medicine, and the society. Normal gene properties; Gene Expression and regulation. University of Leicester (6) defines gene expression as a process where the genes nucleotide sequence directs synthesis of proteins and production of cell structures. The process involves two main stages, First is transcription, a process that involves production of messenger RNA (mRNA) .Transcription also involves the processing of the resultant mRNA molecule. Second is translation, a process where mRNA directs protein synthesis and a further processing of the protein molecule (6).Gene regulation involves cellular processes that regulate manner and rate of gene expression (6). Gene regulation first involves regulating the transcription rate regulating how RNA molecules are processed and regulation of stability in mRNA molecules(6). Gene structure and localization The gene structure has elements such as the protein coding sequence and a sequence for regulation of gene expression. Furthermore, they are expressed by a promoter sequence.RNA polymerase and transcription factors bind and allow for the recognition of promoters to initiate transcription. Weakly transcribed genes have a weak promoter sequences that rarely initiate transcription while genes that are strongly transcribed have promoter sequences that are strong and ensure a perfect bind to initiate transcription to proteins (6).Genes are located on the chromosome in a linear fashion like beads on string(6). Examination and analysis of gene dysfunction (common and rare mutations) Regina (8) states that a nucleotide sequence in the DNA undergoes changes that lead to gene mutation . The alteration affects either one-nucleotide sequence or the gene segments in a chromosome. Often when a nucleotide sequence is altered, it results in the formation of nonfunctioning proteins. The most common types of mutations are the point mutations .They include silent mutations, which do not produce a visible change in the protein.In addition to that, misense mutations allow for the production of different amino acids. Finally, nonsense mutations alter the nucleotide sequence leading to the coding of a stop codon that stops transcription.(8). Base pair insertions or deletions occur when nucleotide base pairs are deleted or inserted to the original gene sequence (7).The Human Genome institute states that almost all diseases have a genetic factor. Diseases are caused by various kinds of mutations in the gene (7). Ellen (9) summarizes that proteins are versatile macromolecules since they perform an array of functions. Proteins are involved in growth and maintenance of tissues. Proteins provide energy and they are involved in hormone production. Hormones regulate functions in the body that relate to many organs. For example, insulin controls the amount of glucose in blood. (9).Enzymes are proteins that catalyze the bodys chemical reactions. Proteins are also involved in the storage and transport of molecules such as haemoglobin, moreover, they form antibodies that fight diseases and infections (9). Primary structural properties of proteins. The primary structure of proteins is generally made up of amino acids. Proteins have twenty essential and non-essential amino acids, which have an amino group and a carboxyl group. This functionality structure enables each amino acid to link to another and form peptide bonds. Peptides are formed when 50 amino acids with short sequences link together while longer sequences form polypeptides or proteins (11).Amino acids have different structures because of the differences that occur in their side chains. Proteins are synthesized during transcription and translation. Posttranslational modifications such as phosphorylation and glycosylation are important for function of a protein (4). Secondary Structure The secondary structure depend on hydrogen bonding. The structure is divided into an helix and a sheet, the alpha helix is right handedly coiled with an external extension inside chain substituents of amino groups. Formation of hydrogen bonds involves the oxygen molecule of one peptide bond and hydrogen molecule of another peptide bond and these bonds ensure the stability of the structure (11). sheet hydrogen bonds are formed between two strands. The sheets can be parallel or anti parallel based on similar or different directions of the N-terminus or C- terminus strand. An antiparallel sheet has well aligned hydrogen bonds therefore; it is more stable than a parallel sheet (11). Tertiary and quaternary structural properties of protein. This is the general 3-D shape of a protein. The protein twists in a manner it can attain a low energy state or maximum stability (11).The protein 3D shape appears random and irregular but it is shaped by several stabilizing forces such as disulfide bridges, hydrogen bonds, and salt bridges because of the interaction of bonds between amino acids side chains(10).Protein molecules are composed of many protein subunits that interact and arrange themselves to form an aggregate bigger protein complex known as a quaternary structure (4). Protein dysfunctions; Effects on protein function and structure. Protein dysfunctions might induce a loss of a function or a gain of a function, furthermore, they can cause a complete loss of protein or reduction on the ability of the protein to perform its functions (4). Classification of proteins mainly depends on the similarities of amino acid sequences and structures. The classification is aimed at determining evolutionary relationships in proteins. Proteins are classified into class, fold, super family, family, protein domains, species and domain. The taxonomy enables a proper understanding of drugs, production of vaccines, or antibodies for biomedical research (7). Description of Cerebral amyloid angiopathy.(CAA) The disease is signified by the deposition of amyloid on cortical arteries and leptomeningeal arterioles and it is associated with old age.Hereditary forms of CAA are rare in the population, they are more acute and severe on the onset, and furthermore, they occur in the young people .The action of secretases on the amyloid precursor protein results in the deposition of amyloid peptides, proving some aspects of pathophysiology of Alzheimers disease (13). Symptoms. Fifty percent of individuals who get the disorder are over 70 years therefore it can be asymptomatic since it can be displayed as evidence of normal aging. Deposition of amyloid in the cerebral blood vessels causes their rupture, this leads to asymptomatic micro bleeds. Amyloid deposits that lead to ischemia. Clinical manifestations related to it such as leokoaraiosis, incomplete infarction, and cerebral infarction obliterate the vessel lumen. This can lead to unconsciousness, cognitive decline or death. Focal neurological deficits and seizures occur in CAA patients (13, 12). Diagnosis An affected brain tissue obtained via brain biopsy or at autopsy is used in histological investigations, often CAA evidence is found in postmortem investigations. Furthermore, another proposed non-invasive method of diagnosis is emission tomography imaging with a compound that binds amyloid. Histological diagnosis requires the use of special stain under light microscopy. The standard staining method of amyloid has been Puchtler alkaline Congo red stain but it has a low sensitivity (15). A more sensitive Thioflavin S stain can be used with Congo red stain. Fluorescent microscopy and immunohistochemistry with antibodies specific for a particular precursor protein can be used as a diagnostic tool(15). Prevalence and Burden The disease is a common clinical entity and there have been frequent findings in pathology among the elderly people.According to an analysis done on brains at Harvard Brain Tissue Resource Center, 2.3 % of 65 to 74 year olds were graded as severe or moderate carriers 80% in 75 to 84 years old and 12% for those over 85 years old. It can be present in 10% to 40% of most of the elderly brains. (14). Cerebral amyloid angiopathy ; Molecular basis of the disease. The disease is characterized by a point mutation, which translates to Leucine for a Glycine change at position 68 of cystatin C protein. In the hydrophobic core of the protein, a mutated residue, and the substitution of the amino acid affects the molecule stability thus destabilizing the alpha helical structure, which leads to a molecule that is more unfolded with an ability to form dimeric assemblies. A study on the crystal structure of the molecule reveals that through the three-dimensional domain swapping, dimerization occurs which leads to the formation of larger structures that resemble amyloid (12). Cellular and physiological basis of disease Cerebral amyloid angiopathy is a disorder that damages the adventitia and media of the leptomeningeal and cortical vessels, stenosis of lumen and it enhances fragmentation of internal lamina. This process of disease manifestation leads to microaneurysm, fibrinoid necrosis thus predisposing the body to cerebral hemorrhage. The disorder also induces changes in the brain that include lobar cerebral hemorrhage, cortical ischemic infarcts, leukoencephalopathy and plague deposition in tissues (13).Ravi (13) argues that the mild condition of the disease affects a smaller portion of the superficial cortical and leptomeningeal vessels while in severe conditions of the disease, there is a significant amyloid deposition in arteries and arterioles. The most affected are medium sized arteries with deposition of amyloid outside the tunica media to tunica adventitia(13). Evidence based discussion of the current and future potentials for treatment Masahito(14) states that since there are no therapies for modifying the CAA disease, current and future potential for the treatment lie in the presence of biomarkers and risk factors. Deposition of cerebrovascular amyloid is a primary target for treatment and prevention. Therapies for anti amyloid include Ponezumab, a monoclonal antibody which specifically attaches itself to the carboxyl region in the A40.Currently, the therapy has been applied to individuals with CAA.A trial is going on currently to assess the tolerability, safety and efficacy of ponezumab in adults(14). Several non-genetic factors such as hypertension and thrombolytic anticoagulation have been associated to CAA, and they are to be avoided. Future considerations in regards to treatment and preventation should involve protection of blood vessels walls against causes of degradation and research on anti-amyloid therapies. References World Health Organization. Gene and Human Diseases[Internet]. no date[cited 2017 August8] . Available from: https:// who.int/genomicss/table. Anthony JF, Jeffrey HM, David TS, William MG. An introduction to genetic analysis.7th New York: WH Freeman; 2000. Ian M. All about DNA and proteins[Internet]. 2017 [ updated 2017 Apr 7; cited 2017 August 1]. Available from www.exploredna.co.uk/allaboutdna. Tropp B. Biochemistry; Concepts and Applications. First Edition. London. Brooks Cole Publishing Company. 1997. US National Library of Medicine. CST3 Gene.Internet]. 2011 [updated 2011 Mar; cited 2017 August 6]. Available from https:// ww.ghr.nlm.nih.gov/gene/CST3. [Accessed 6th August 2017] University of Leicester. Gene expression and regulation [Internet]. 2009[ cited 2017 August 7].Available from https://ule.ac.ku/projects Maston G, Evans A, Green M, Sara K. Transcriptional Regulatory element in the Human Genome .Annual Review of Genomics and Human Genetics[Internet]. 2011[updated 2017 June 5; cited 2017 August 7]. Available from https://doi.org/10.1146/annurev.genom.7.080505.115623 Regina B. Gene Mutation [Internet]. 2017[updated 2017 February 8; cited 2017 August 7]. Available from https://thought.com/genemutations. Ellen T. 6 Primary Functions of ProteinsInternet]. no date [cited 2017 August 8]. Available from: https:// healthlivingsfgate.com/6 primaryfunctionsofproteins5372.html Berg JM, Tymoczko JL. Biochemistry 5th Edition: New York: WH Freeman Publishers; 2002. Particle Science, Drug development Services. Protein Structure[Internet].no date[cited 2017 August 7]. Available from www. Particle.science.com/news/technical briefs/2009/protein structure.]. George G, Yasushi T, Hirosaki A. Cerebral Amyloid Angiopathy, and Alzheimers disease. U.S National Library of Medicine[Internet]. 2011[cited 7th August 2017]. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964669 Ravi S. Cerebral Amyliod Angiopathy[Internet]. no date[cited 2017 August 7] Available from: https:// emedicine.medscape.com/article/142720 overview. Yamada M. Cerebral Amyloid Angiopathy. Emerging concepts. Journal of Stroke[Internet]. 2015 [cited 2017August 8]. Available from: https://ncbi.nlm.nih.gov/pmc/articles/PMC4325636. Allesandro B, Steen M. Cerebral amyloid angiopathy. Journal of Clinical Neurology [Internet]. 2011 [Accessed 8th August 2017] ; 7 (1): 1-9. Available from www.ncbi.nlm.nih.gov/pmc/articl

Wednesday, December 4, 2019

Whats Worth Knowing free essay sample

An analysis and review on Wendy Lustbaders book `Whats Worth Knowing about life experience gleaned by the older generation. The paper reviews and analyzes Whats Worth Knowing` by Wendy Lustbader, a geriatric social worker who met many people of the older generation and wrote a book based on the experience they gleaned in their eighty or so years of living. The paper shows how the book uses ordinary individuals to make up stirring recollections. `The book captures the pulse and flavor of the individual contributors; every one of the single-paged accounts reverberates with a spirit of great generosity and sincerity. A short, stirring biographical note and sometimes a photo accompanies each story. In her book Lustbader asks, what factors make life superior. Moreover, how do we live it? What do we know now that we wish we had known when we were young(er)? What advice would we give a young(er) person just starting out in life? Has anyone in our life taught us a valuable lesson? What was that lesson? If we could live our life over again, what would we do differently? What would we keep the same?`